Oxidative stress and antioxidants: diagnosis and therapy

The goal of this symposium is to provide a forum for scientific and technical exchanges of the recent advances in the diagnosis and treatment of oxidative stress with implications in human health. The section will bring together scientists from different fields (chemistry, biochemistry, biology, materials science) to discuss the latest developments, challenges and opportunities in this exciting area of research. Novel therapeutic approaches for the treatment of oxidative stress diseases as well as strategies for measuring oxidative damage (DNA damage, release of reactive oxygen species, etc) in vivo and in vitro will be discussed. The symposium will also include presentations on mechanistic studies of natural antioxidants and investigations of new materials possessing interesting antioxidant/free radical scavenging properties as therapeutic agents in the treatment of medical diseases related to reactive oxygen species, such as spinal cord injury, stroke and neurological disorders. Topics of particular interest include (but are not limited to):

• Biological mechanisms in oxidative stress related diseases
• Genotoxicity and cytotoxicity
• Evaluation of antioxidant activity, oxidative damage and reactive oxygen species
• Therapeutic approaches involving antioxidants
• Novel antioxidants and their mechanism of action
• Nanoparticle-induced oxidative stress
• The role of antioxidants in human health

Session organizer

Dr. Silvana Andreescu is Assistant Professor in the Department of Chemistry and Biomolecular Science at Clarkson University. Dr. Andreescu's research interests include investigations of biomimetic materials with antioxidant properties for diagnosis and therapeutic applications in biomedicine, and development of practical biosensors for environmental and clinical monitoring. Other interests include in vivo toxicity studies of engineered nanomaterials and development of electrochemical probes for in vivo measurements of neurological activity, nanoparticle-induced toxicity and oxidative stress.

Confirmed speakers

• Dr. James F. Rusling, Professor of Chemistry and Cell Biology, University of Connecticut.
• Dr. Omowunmi A. Sadik, Professor, Department of Chemistry, State University of New York at Binghamton, Binghamton, NY.
• Dr. Ana Estevez, Professor, Department of Biology, St. Lawrence University, Canton, NY.
• Dr. Artem Melman, Professor, Department of Chemistry and Biomolecular Science, Clarkson University, Potsdam, NY.